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science-sculpt · 2 months

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The Immune System's All-Star Team: The Mighty Cells That Protect You

Your body is like a bustling city, constantly facing threats from outside invaders like viruses and bacteria. Thankfully, you have a team of dedicated defenders keeping you safe: your immune cells! Our immune system is a marvel of biological defense, tirelessly safeguarding our bodies from harmful invaders like bacteria, viruses, and parasites. At the forefront of this defense are numerous types of immune cells, each with its unique functions and capabilities. Did you know the average adult has about 2 trillion white blood cells, which contain most immune cells? That's more people than live in China! These tiny warriors come in different shapes and sizes, each with unique superpowers to protect you. Let's meet some of the key players:

The Innate Force: First up, we have the innate immune system. This frontline defense acts fast and nonspecifically, providing immediate protection against any threat. The key players: 1. Neutrophils: Think of these guys as the city's SWAT team. They're the first responders, rushing to attack invaders with toxic chemicals and swallowing them whole with their arsenal of enzymes! These are the most abundant immune cells, are short-lived but highly effective. Unfortunately, they die in the fight, leaving behind a green gooey mess (pus) that signals infection.

2. Macrophages: These are the veterans, the wise generals of the immune system. They go beyond mere engulfing, processing antigens (foreign molecules) and presenting them to other immune cells for recognition and attack. They also act as scavengers, cleaning up debris and orchestrating healing. These are the cleaners and recyclers. They gobble up dead neutrophils, debris, and even worn-out cells, keeping your city sparkling clean.

3. Natural Killer (NK) Cells: These are the ninjas of the immune system. They silently patrol, sniffing out suspicious cells infected with viruses or even cancer and eliminating them with a swift punch. The Adaptive Arsenal:

The Adaptive Arsenal: If the innate system fails, the adaptive immune system steps in. This highly specific defense remembers past encounters and tailors its response to each unique threat. The cells of adaptive immune system are:

B Cells: These are the antibody factories, producing highly specific proteins called antibodies that neutralize pathogens and toxins. Each B cell produces a unique antibody, like a lock and key, targeting specific invaders. They whip up special proteins called antibodies that lock onto specific invaders, like sticky notes, marking them for destruction.

T Cells: These are the generals, coordinating the entire defense. There are different types of T cells:

Helper T Cells: These are the commanders, directing and coordinating the immune response through chemical signals. They activate B cells, macrophages, and other immune cells, orchestrating a multi-pronged attack.

Cytotoxic T Cells: These are the elite soldiers, directly targeting and eliminating infected cells or cancer cells. They recognize and bind to specific enemy markers, unleashing a lethal attack.

Memory T Cells: These are the veterans, remembering past encounters with invaders and helping the immune system respond faster next time.

The Unsung Heroes: Beyond these main players, numerous other immune cells contribute to our defense. These include:

Dendritic cells: These antigen-presenting cells capture and process pathogens, presenting their fragments to T cells for activation. They're like the scouts, gathering enemy intel and relaying it to the command center.

Mast cells: These cells reside in tissues and release inflammatory chemicals in response to allergens or parasites. They're like the alarm system, alerting the immune system to local threats.

Eosinophils: These specialize in fighting parasitic infections, releasing toxic chemicals to neutralize them.

Basophils: These are involved in allergic reactions and contribute to wound healing.

The beauty of the immune system lies in its intricate collaboration. These diverse cell types work together in a complex and beautiful dance, each playing a specific role to achieve a common goal: protecting our health. They communicate extensively through chemical signals, creating a complex network of interactions. Imagine B cells producing antibodies that bind to a pathogen, flagging it for destruction. Macrophages engulf and eliminate the tagged pathogen, while T cells coordinate the attack and eliminate any infected cells. Dendritic cells present captured fragments to T cells, priming them for future encounters. This seamless cooperation ensures a swift and effective response to any threat.

Your immune system is constantly learning. Each time you get a vaccine or fight off an infection, your immune cells create memory T cells, making you more resistant to future attacks. Understanding these cellular heroes can help us appreciate the incredible machinery that keeps us healthy and appreciate the importance of maintaining a strong immune system. It also allows us to make informed decisions about supporting our immune system. Maintaining a healthy lifestyle, getting adequate sleep, managing stress, and consuming a balanced diet can all contribute to a robust immune response.

#science sculpt #life science #science #biology #biotechnology #artists on tumblr #immunology #immunotherapy #immune cells #b cells #t cells #neutrophil #macrophages #immunity #health and wellness #medicine #healthcare #illustration #illustrative art

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incorrect-immunology-facts · 9 months

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Wait, MPreg stands for regulatory macrophage, right?

#macrophages #mpreg #immunology shitposting

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12biscuits · 1 year

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Sometimes, a scientist finds a wholly new immune cell. Only to turn out, this is just a macrophage in different tissue

#science #science humor #meme #nerd #macrophages

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homeostasister · 1 year

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A Th2 Anthem

We will bring the floods, the pain and the violence

We’ll summon the soldiers of russet and violet

To sound the sirens and slay the giant

And when the battle is over, in the damage we’ve wrought

We’ll call upon the sentinels

To stay the weather and build back better

#immunology #th2 #type 2 immune response #immune cells #t cells #eosinophils #basophils #macrophages #mast cells #song I made up #biology

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firstmedicaldiagnosticspvtltd · 4 months

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We aim to Prevent You From Falling Sick At An Early Stage | FMD

When an astrologer predicts future events for you, the sense of excitement and amazement is undeniable, isn't it? It's an experience that captivates and intrigues, offering a glimpse into the possibilities that lie ahead. When both positive and negative factors that could impact your life are known beforehand, you are better equipped to make informed decisions.

But what can happen when you know the future of your health? Knowing the future of your health empowers you to proactively make the right decision that positively influences your overall well-being. It allows you to adopt preventive measures, make lifestyle adjustments, and prioritize self-care, ultimately steering you toward a healthier and more fulfilling life. By gaining insights into potential health outcomes, you make rational decisions and actively take part in shaping a future where your well-being is your priority.

How First Medical Diagnostics Empowers Early Detection

At First Medical Diagnostics, we're more than just a healthcare provider; we're your partners in well-being. We understand that staying healthy isn't just about reacting to illness – it's about being proactive, taking charge, and living your best life. Our mission is deeply rooted in this philosophy. We're not only here to diagnose diseases and symptoms but to be your true companion in prevention.

Imagine a healthcare experience where we work together to identify potential health issues in their earliest stages. It's like having a personalized early warning system for your well-being. By catching concerns before they have a chance to disrupt your life, we empower you to stay in control and live each day to the fullest.

Why Early Detection Matters?

Early detection is a game-changer in healthcare. It can significantly improve patient outcomes and increase the chances of successful treatment. By identifying diseases or conditions at a primary stage, healthcare professionals can intervene sooner and implement preventive measures. It can also lead to cost savings, as treating a disease in its early stages is often less expensive than treating it in its advanced stages.

Early detection of a health problem leads to prompt intervention, often with less invasive and more effective options. This can result in better health outcomes and a higher chance of successful treatment. For example, if a person notices early symptoms of cancer and seeks medical attention, they may be able to receive targeted therapy or surgery, which can be less invasive than later-stage treatments like chemotherapy. For this, we offer a PanTum Test that helps in the early detection of cancer cells and prevents you from suffering in the future.

Better treatment results: There is a substantial increase in the chance of a full recovery and a successful course of treatment with early intervention. Early intervention allows for the identification and management of health conditions at their early stages, when they are most treatable. By detecting and addressing problems early on, medical professionals can prevent the progression of diseases and minimize potential complications.

Reduced burden on healthcare systems: By preventing serious illnesses, we alleviate the strain on hospitals and resources, benefiting everyone. This reduction in burden allows healthcare systems to allocate their resources more efficiently, ensuring that those who truly need medical attention receive it promptly. It also helps in decreasing waiting times for treatments and surgeries, improving overall patient care.

Specialized Tests, Powered by German Expertise:

Our specialized tests bring you the latest in German expertise, ensuring accuracy and reliability. We don't stop at just offering test results instead our group of medical specialists will assist you at every turn, providing:

Professional interpretation of your test results: We'll discuss the significance of your test results and how they may affect your health.

Personalized consultations: After talking about your lifestyle and risk factors, we'll create a strategy specifically for controlling your health and lowering your chance of getting sick in the future.

After the initial consultation, we're here to help with ongoing support and monitoring. We'll make any necessary changes to your plan and still provide ongoing monitoring.

Investing in Your Future Well-Being

Investing in early detection is a future-oriented investment. It's about assuming responsibility for your health and giving yourself the tools you need to live a longer, better life. First Medical Diagnostics is dedicated to giving you the resources required to do this.

We believe that everyone should have access to state-of-the-art medical treatment and individualized diagnostics. For this reason, we provide customizable testing plans and alternatives to fit your requirements and price range.

For more information,

Call us at +91 8800929600

Visit us at www.fmdindia.in

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cailynnjohnson · 9 months

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Macrophages are innate immune cells characterized by evolutionarily conserved functions, such as host defense against infection and tissue homeostasis. Macrophages present a high plasticity grade, being able to change their phenotype in response to environmental stimuli. They play central roles during development, homeostatic tissue processes, tissue repair, and immunity. Furthermore, it is recognized that macrophages are involved in chronic inflammation and that they play central roles in many diseases, including cancers, autoimmune diseases, cardiovascular diseases, and tuberculosis.

#macrophages

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bpod-bpod · 3 months

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Macrophages in Development

Macrophages – a type of inflammation-linked immune cell – regulate metabolism and growth of developing intestinal tissue in a lab-grown organoid model

Read the published research article here

Image from work by Andrew T. Song and colleagues

Centre de Recherche, CHU Sainte-Justine, Montréal, QC, Canada

Image originally published with a Creative Commons Attribution – NonCommercial – NoDerivs (CC BY-NC-ND 4.0)

Published in Cell Reports, December 2023

You can also follow BPoD on Instagram, Twitter and Facebook

#science #biomedicine #immunofluorescence #biology #organoids #intestines #gut #macrophages #developmental biology #embryonic development

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parrotssuchto · 1 year

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#peasantry

#peasantry #coronary #saturnine #macrophages #bewhiskered

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medicomunicare · 2 years

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Growing bad due to bad influences: here go guilty astrocytes hosing the cancer mass with cholesterol

Glioblastoma is an extremely aggressive and invasive brain cancer, for which there exists no known effective treatment. The tumor cells are highly resistant to all known therapies, and, sadly, patient life expectancy has not increased significantly in the last 50 years. A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma by combining existing molecules. The…

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#astrocytes #blood-brain barrier #brain cancer #brain cortex #cancer cells #cellular energy #cholesterol #glioblastoma #macrophages

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hemantjimin · 2 years

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कार्डियक अटैक के बाद हमारा हार्ट खुद कर सकता है अपना ‘इलाज’, नई स्‍टडी में दावा

The human body works on a system in which it can take care of itself. Scientists are doing research on how the body repairs itself after a heart attack. The scientists aim to uncover perspectives that will lead to more effective cardiovascular therapy. At present, a new research has found that the body’s immune response and lymphatic system, which is part of our immune system, have the ability to…

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#cardiac arrest #cardiac attack #efferocytosis #heart #human heart #macrophages #new study #science news in hindi #study #vegfc

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teabutmakeitazure · 1 year

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Congratulations on 1000 followers, 1000 mouths to feed, and 2000 watchful eyes (｢• ω •)｢ Couldn't happen to a better writer ♡

I saw you sneak Illumi on that list. I am very frightened of the needle man. Can I request something with the first time Illumi realizes he is obsessed with darling?

Perforate and Permeate

>Yan! Illumi x Fem! Reader

>Word count: ~3.4k

Red flags start appearing in the form of odd piercings on taxi drivers. The feeling of something horribly off surrounds you, but in the end, some people are always powerless, aren't they?

The first red flag of the evening was the creepy taxi driver. There seemed to be some sort of yellow ball stuck to the skin on his neck, and his movements and speech were somewhat robotic. The second red flag was that he offered you a ride without you even calling for one.

Thankfully, the evening rush hour helped you get away from the peculiar man, and you slid into the subway train, hidden and safe among the numerous people around you. Ironically enough, it felt a little hypocritical to find comfort among the number of people since you were always adverse to crowds. The smell of sweat and close proximity of human beings made you a little nauseous, but right now it felt safe.

The third red flag comes in the form of your apartment building’s watchman being absent. He never takes a day off and always ensures that the other watchman - the man who usually works as the receptionist since for some reason there’s a desk and everything in the lobby - takes his place while he’s away for food or such.

Neither men were there and as you press the elevator button to your floor, you catch a shadow in the corner of your eye before the doors close. The fourth red flag is that your apartment windows are open. Not all of them, but the living room windows are open. You’re absolutely certain you had left them closed when you left. You could even swear on it.

Nevertheless, some sort of dismissive hope deludes you into believing that the wind opened them and you don’t dare come any closer. The reminder to check their locks is pushed into the back of your mind when you fall onto your bed face first. Silence envelopes you, its warm hands granting you the comfort of your home.

Despite how quick the comfort came, all relaxation leaves your bones when your phone rings. As you accept the call and press your phone to your ear, you realise you almost drifted off. Your mother’s voice greets you before turning into a scolding one when you tell her you just got home.

The conversation goes as it usually does, your nerves calming down despite the subtle feeling of not being alone. You don’t blame your scepticism. Ever since you moved out, you’ve always been careful and paranoid. Maybe it has to do with preferring silence and being around less people, but you don’t like the lonesomeness and silence as much as you thought you did.

You say goodbye to your mother on the phone, and sit up, groggily making your way to the kitchen. The silence of the apartment unnerves you, so you turn on your phone’s flashlight and check every single room and cupboard of the house, leaving all the light bulbs on.

The apartment is now fully illuminated and the TV plays some random news show while you cook. It makes for good white noise and you don’t feel as alone anymore.

But you still feel watched.

The curtains are promptly drawn over the windows.

Thankfully, the feeling goes but quickly returns when you sit down to eat dinner. The panic that arises constricts your throat, heart beating in your throat and you immediately dial your mother again, praying that the paranoia dies down.

It doesn’t. She never picks up.

Three phone calls later, she picks up but excuses herself saying that she’s going out for lunch with your father. The time zone difference makes you frown, realising that you're ruining her weekend with your baseless paranoia.

Dinner gets your attention back, but something seems to have its attention on you.

You're cognizant of the sounds coming from the street, television muted. The drip drip from the kitchen sink sings the vocals while the refrigerator buzzes the music. Exhaling, you pay attention to the noisy details, dinner finished and an empty plate in front of you.

The feeling goes away soon, but comfort doesn't return.

The first red flag of today's evening follows behind you. A man with his hoodie hiding half his face is trailing behind you, and you're briefly wondering how dense he must be to not realise that you're leading him in a circle for the fourth time. You don't mind the extra walking, but it's pretty annoying.

Should you lead him to a police station? Losing him doesn't seem to be an option. He's persistent. Even in the fifth circle, he's casually walking behind you.

You go ahead with making your way to a nearby station, but he slips away when it's in sight. Your eyes watch the man as he heads the other way, an uneasy feeling stirring in your chest at the loss of someone's eyes on you. As you make your way back to the subway station, you contemplate walking home instead. Maybe you could drop by a café or even pick up dinner from somewhere.

However, a second red flag appears while you are in your thoughts. A taxi stops in front of you when you're scrounging around your bag for your phone and the window pulls down to reveal a taxi driver with a strange yellow piercing between his eyebrows.

The driver offers you a ride, and you stare at him dumbfounded. You didn't call for a taxi. A few passer-bys send you confused looks, but you brush it off. The man is promptly shut down and you walk away, mentally cursing yourself over the lack of crowd on the street.

Almost as though on cue, a lady grabs your arm. Her grip is unyielding and she frantically explains how you need to come with her. A familiar yellow piercing on either side of her neck greets you when you turn to look at her, but any composure you have quickly dissipates when she starts pulling you.

It takes everything you have in you to pry yourself off and run in the other direction. The few people that did stare at you turn away when they see you running, and honestly you don't blame them. No one wants to get tangled up in something like that.

By the time your legs start hurting, you're almost home. There's no time to pick up anything from a restaurant so you make a mental note to order in instead. As you walk with your phone in hand, the situation dawn's on you. Three red flags already. You don't even want to know what the fourth one will be.

But alas, the heavens never hear your silent pleas and the fourth red flag stands in the watchman-less lobby of your apartment building. You hadn't seen either men today as well, and simply seeing the person who casually leans against the wall with eyes fixed on you is making your heart do literal backflips inside your chest.

"[Name]."

The simple greeting makes you freeze. Hands grip your bag tighter as you look into his bottomless eyes and greet him back with a simple hello. He doesn't seem to mind your nervousness and gets straight to the point.

"I wanted to see you. It's been quite a while."

Your finger remains on the power button of your phone, ready to press it five times at the earliest notice to send SOS messages to your friends. Upon receiving no response, he continues, trying not to eye your deathly grips on your belongings.

"How was your day?"

"It was… fine." Voice meek, you don't know what to say to him. It's not everyday you see a person such as himself. "How… have you been, Illumi?"

The question seems to perk him up. "I'm not quite sure, but I suppose I've been alright. I do want to ask you something. Why are you holding your phone and bag so tightly?"

The muscles on your legs go taut, and you briefly glance at the elevator door thinking you could make a run for it. However, the reminder of Illumi's occupation mocks you. Of course a hunter wouldn't let you go so easily.

"I'm not sure." Your words are unsure as you speak. "I guess I'm not feeling very well."

"Should I get you medical attention?"

"No. Not that kind of not very well. I just feel a bit down, that's all."

He seems to have understood something because he's nodding. "I see. If there's nothing wrong with your physical health, it'll go away. Make sure to rest properly and you'll feel better."

"Thanks. I'll go to bed early tonight."

"Are you free right now?"

Free? Does he want something? You're no help to a hunter. "I'd like to get to bed as soon as possible, but I'm willing to hear you out."

Your grip on your phone loosens a bit, and Illumi immediately takes a few steps closer. Hardly a foot of space is left between the two of you, but before apprehension can return, he's demanding all your attention with his words.

"May I have your phone number?"

What?

"My… phone number?"

He nods. "Yes. Your phone number."

The dumbfounded look on your face makes him blink at you owlishly.

"I was wondering whether or not it would be appropriate for me to ask for it. I suppose I settled with ignoring the thought."

Did he… really just admit that?

"Um, alright. I don't see why not." You know where I live anyway, the voice in your head continues.

You share your contact information with Illumi, but you have no idea why he wants it. His intentions are as clear as muddy water. It doesn’t make you feel any better, but if nothing, at least he asked you for it. With his licence, he could have obtained your number with ease like how he ended up in your apartment's lobby. You give him only a few points for human decency.

When he’s done saving your information on his phone, a satisfied look is on his face. The silence of the lobby remains as you wait for him to finally let you leave. That is to say he doesn’t request to visit your apartment.

“I think that’ll do.” Illumi looks up, head tilting slightly when he sees your exhausted expression. “You should rest. I won’t stop you. Just seeing you this evening is enough for me. We can talk some other time.”

Talk? What would you both even talk about? The only reason you know him is because some target of his was your work client and he scared him off. Honestly, never hearing from that man again is one of the best things that happened in your life.

“Sure,” you reply with a very obviously unsure voice. “I’ll see you later then.”

Illumi waves you off and as you step towards the elevator, you feel a little shameful for not inviting him for dinner. But then you remember that you live alone and he’s an adult man. Perhaps it’s better to not do so.

As you press the button, you glance back at Illumi down the lobby. He's waving at you, so you wave back. The door starts to close and the expression on Illumi's face changes. Lips curl upwards, eyes crinkling as well.

When the door closes, you're thankful for the distance. You never want to see that horrifying grin on his face again. It sent shivers down your spine and it seems like the creepy smile is now engraved into your brain.

Had you not been in the elevator, you would've ran out the lobby. Perhaps some people are better off expressionless after all.

It's been an entire day since Illumi took your number. There's been no contact, no message, nothing. As you stare at your phone sitting in front of you on the sofa, you think back over today's evening bitterly.

There was another taxi driver with the same yellow piercing. Added to that, an old woman with the same piercing had approached you and asked to walk her home. You declined. Though it felt bad to say no to an old lady, you didn't want to possibly find any unwanted trouble.

Besides, there's something definitely wrong going on. After the old lady, you found the watchman in the lobby. Even he had a piercing on his face, in between his forehead to be precise.

You didn't bother to reply to his greeting this time. There was something off about his smile.

Maybe you should move out as soon as possible.

However, that's not what's bothering you. It's the fact that there have always been four red flags. This evening, you only came across three.

The thought of an impending fourth one makes you feel nauseous. You're home now, back to safety. There has never been anything bad between these four walls, so why would there be anything now?

Maybe you missed counting a fourth one. Yes. That's it. You just missed one red flag. The thought doesn't do much to console you, but it's enough to allow you to sleep when your head hits the pillow. Unfortunately for you, that doesn't last very long.

The feeling of a pair of eyes wakes you up with a startle. You immediately throw away the covers and run to the switch, turning on the lights. Nothing. The same goes for the rest of your apartment. All the lights are on but there’s nothing out of place.

Are you going crazy?

It must have been a bad dream. You still feel watched, but that’s just because you just woke up. Water. You need some water.

The glass is quickly emptied as soon as you fill it, and now you stand alone in the kitchen, the silence of the night and the refrigerator’s hum your only companions. The kitchen counter is cold underneath your lingering fingertips, and begrudgingly, you part with it.

Sleep doesn't come back easily. At least half an hour must’ve passed with no sign of slumber’s gentle embrace, so you get up and turn off the bedroom light. The door is then left open only a little bit to let some light from the living room bleed inside the room.

It doesn’t help much, but your eyes feel less burdened.

Upon turning to the other side and nuzzling into the sheets further, the lessened burden seems to increase again. There’s someone resting their face on the mattress, body probably sitting on the floor and this person’s eyes seem to be fixed on you.

It takes you blinking a few times and sitting up to realise this isn’t a dream.

By the time your eyes have completely blinked away any sleep, a hand is slapped over your mouth to stop you from screaming. Your chest heaves as you follow the arm to the body it’s attached to and finally the face.

Illumi.

“Pardon me if I woke you up. It wasn’t my intention.”

The mattress dips as he joins you on the bed. If the circumstance wasn’t unfortunate enough, he’s now literally hovering over you with one of his knees between your parted legs under the blanket. Long black hair cascades around his face as he leans in, large eyes observing your features.

You blink at him as your breathing settles down. The lack of action from Illumi’s end does help your nerves calm down a little, but the threat of an obviously more powerful man literally above still remains.

This is your fourth red flag.

The weight of his observant stare weighs you down, the feeling of a boulder on your chest making you sink backwards into the bed. All that you see are Illumi’s large, dark eyes. It’s suffocating and you want to scream, but the sound dies in your throat before he even lets go.

You don’t dare make a single noise as he sits up straight on your thighs.

Illumi briefly breaks eye contact, eyes dropping down to your collarbones peeking from your neckline from the dishevelled state before his eyes go back up to yours. The weight of the boulder had lifted during that time, but with his eyes back on you that weight goes to your consciousness.

“I suppose I should commend you for not screaming. Seems like you’re quick to understand.”

All he gets in reply is your nervous gulp.

“You require an explanation, don’t you?”

This time, he tilts his head at your lack of response.

“I gave myself an ultimatum. Four tries every evening for every working day of this week are all I have to work with. If your refusals of my lenient methods bother me, then I must get to the bottom of the feeling. If I am not bothered in the slightest, I must stop wasting my time.” Iluumi pauses, possibly in anticipation of some sort of response, but continues. “I suppose my presence here at this hour explains which conclusion I had come to.”

He waits again for a few moments but ends up explaining his own words himself when you’re still frozen in what he thinks is shock. “Your refusals bothered me. I can’t be certain why. Even your less enthusiastic response to me asking for your phone number bothered me.”

You’re still staring at him. Mind barely processing the words. Illumi is in your room in the middle of the night. Illumi is a hunter, a potentially dangerous person, and he’s caged you to your own bed. This is the most vulnerable you’ve ever been in your life, yet you can’t even bring yourself to cry over the absolute fear you feel because of the intensity that keeps growing and radiating from Illumi.

“You occupy my thoughts more than I would prefer, and the only cure I found for that is to watch you when you’re home. No other activity soothes it.”

His index finger and thumb hold his chin as he continues thinking over the matter, but his eyes are still fixed onto you. When his eyes widen slightly, the intensity you felt grows dramatically and you have to reflexively cover yourself till the top of your head with the blanket to not end up asphyxiated.

A hand gently pulls down the cover till your chin, and luckily, the intensity mellows enough to allow you to breathe.

“I came here tonight to understand why trying to sleep on my own causes me distress. It’s like I search for you in my own bed, and the lack of your presence makes me restless.”

He leans in, hands sinking into the mattress on either side of your hips and you instinctively shrink into yourself. Voice perfectly even, the tone betrays the depth of his words. “I talked to my mother about this feeling and came to a conclusion. I’m in love with you.”

Sweat starts to bead at your forehead, but Illumi’s eyes refuse to allow you any reprieve. One of his hands sneak up your body, fingertips gently tracing the outline till his hand lightly wraps around your throat. The grip is non-existent but the threat of a not so well meaning squeeze still exists.

“All I need to do is squeeze. A fragile human such as yourself would give in to death in under ten seconds if I do decide to test my grip. However, even the mere thought of it bothers me. Even now, I can’t bring myself to hurt you.”

The hand moves further upwards, cupping your cheek despite the sweat. “At first I thought you were using some kind of Nen to bewitch me, so imagine my surprise when I found out that you’re a non-user.”

You finally manage to shakily exhale through your mouth, but the beating in your heart suddenly becomes too loud when his thumb traces the edges of your lips.

“I thought I should kill you to get rid of your spell, but the thought of you not existing anymore made my chest ache.” Illumi sighs. “Seems like the damage has been done, and it’s quite a lot. With how the majority of my thoughts are about you, I could even claim that I’m obsessed.”

The intensity grows again, and it gets even harder to breathe in the cool room. When Illumi’s thumb forces your lips open and presses down on your tongue, you can only hope you’ll be safe. After all, the look in his eyes is absolutely frightening.

#thank you for the request #it was fun lol #AzureTea requests #yandere hunter x reader #hunter x reader #yandere hunter x hunter #hunter x hunter x reader #illumi x reader #yandere illumi x reader #yandere illumi #why does the title sound like macrophages doing their everyday job

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