Miss you Baby Girl!!! XOXO 😘 MOMMA
Understanding the mechanisms of r-chop resistance in b-cell lymphoma
White blood cells or lymphocytes are the soldiers of our immune system that patrol the body via the lymphatic system. While their primary role is to protect the body by scavenging invaders, they can sometimes go rogue and become the enemy. Lymphoma, a type of blood cancer, results from the uncontrolled proliferation of lymphocytes. They are classified as Hodgkins and Non-Hodgkins lymphomas on the…
Oh look it’s my cancer ridden insides. I start chemo Monday
Today, we got the results from the last PET scan:
PET study with evidence of metabolically active lymphomatous disease in lymphadenopathy described in the thorax, abdomen and pelvis.
I’m feeling fine and relaxed to know that. More on that later.
I’ve been very sad and heartbroken for two weeks. My sweet girl Lily is really sick and was diagnosed with cancer yesterday. She’s still so young only 6. I freakin hate cancer.
And to you my baby girl, I’ll do everything and anything to make you feel better. You just stay strong and fight this. I’ll never leave you my sweet Lily. I miss your energy. Seeing you so weak breaks my heart. I hope you know i love you sooo much.
CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma
Credit: Unsplash/CC0 Public Domain
A significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical trial continue to be in remission five years after receiving the chimeric antigen receptor (CAR) T cell therapy Kymriah, researchers in Penn’s Abramson Cancer Center reported today in the New England Journal of Medicine. The findings represent the longest follow-up…
Blood-clotting protein plays key role in central nervous system b-cell lymphoma
Gladstone scientist Jae Kyu Ryu (right) and his colleagues discover new links between lymphoma growth and leaks in the blood-brain barrier. Credit: Gladstone Institutes
In people with central nervous system (CNS) lymphoma, cancerous B cells—a type of white blood cell—accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels. This disease is quite rare, but…
Lymphoma – What Is It?
About half of all cancers of the blood fall into the category of lymphoma. This is a cancer of the lymphatic cells of the body, which are a major part of the body’s immune system. Leukemia, another cancer of the blood system which can appear in lymphatic cells, is related to, but distinct from lymphoma in a couple of ways. Leukemia is actually a range of disorders that generally effect either the…
Hey y’all. Sigh. Deep breaths. So there was a phone call from University of Michigan hospital the other day. Like I knew that grandma kept getting various tests to see if the infection had spread but I didn’t know it was this bad. They have to put the chemotherapy on pause for 8 weeks while they try to get the new infection under control. By then the lymphoma will be much much worse. And just basically it’s bad news.
Breyanzi approved for certain types of large B-cell lymphoma
Cell-based gene therapy Breyanzi (lisocabtagene maraleucel) has been approved to treat adults with certain types of large B-cell lymphoma who have not responded to other systemic treatment, the U.S. Food and Drug Administration announced Friday.
The chimeric antigen receptor T cell therapy was approved for relapsed or refractory large B-cell lymphoma, including diffuse large B-cell lymphoma,…
What is Mantle Cell Lymphoma?
Mantle cell lymphoma is a subtype of B-cell or B-Lymphocyte lymphoma categorized under Non-Hodgkin’s lymphoma. This type of lymphoma is due to a malignant transformation of the B-cells. These B-cells are part of the immune system and responsible for destroying microorganisms that invade the body. The disease got its name for the malignant B-cells are often found in the mantle zone of the lymph…
I started off this page because I wanted to figure out what was wrong with me. I had all these raging thoughts in my head that I didn’t know what to do with, and the best thing I could come up with, was to write some of it down in a ~mysterious~ (and sometimes not so mysterious) way. My life took a HUGE turn after I started this page and so then I stopped writing or visting tumblr all that often. Then a few weeks ago I found out that I have MALT lymphoma in my stomach and possibly large intestine. Its a fairly new discovery and I feel like I don’t know how to process all these new changes in my life, including constantly going to the hospital and getting treatment. I thought that maybe it was time to go back to writing. I loved the community here and I just hope I stick to my writing and this community long enough to not only help myself but make other feel less alone in their mental health/ cancer struggles/ struggles of living. :) I’m definitely really rusty but I hope that the more I write, the better I can structure my emotions in a clear and concise manner…
Patients with lymphoma treated with B-cell-depleting therapies may have worse outcomes from COVID-19 infection
Credit: Pixabay/CC0 Public Domain
Among patients with lymphoma admitted to the hospital for severe COVID-19, those treated with B-cell-depleting therapies within the previous 12 months had an increased risk of prolonged hospital stay and death, according to results presented at the AACR Virtual Meeting: COVID-19 and Cancer, held Feb. 3-5.
“Patients with lymphoma may develop immune deficiency…
Cancer is the abnormal growth of cells in the body. Cancer develops in the body when the human body’s normal mechanism stops functioning. When Old cells do not die and instead grow out of correct proportion and forming new abnormal cells. Over time, extra cells make a mass of tissues in the body that generally called Tumor.
Treatment of cancer depends on the type, its stage, many factors are taken into account, if abnormal or cancerous cells spread to the nearby normal cells. Today technology is far advanced. Cancer can be cured if detected early or with Developed Treatments, we can provide an easy and comfortable lifestyle or living to patients.
Common types of Cancers:
· Carcinomas begin in the skin or tissues that line the internal organs
· Sarcomas develop in the bone, cartilage, fat, muscle, or other connective tissues.
· Leukemia begins in the blood and bone marrow.
· Lymphomas start in the immune system.
· Central nervous system cancers develop in the brain and spinal cord.
After all, Cancer is just a word, not a sentence.
Cholesterol starvation kills lymphoma cells
Credit: Pixabay/CC0 Public Domain
Scientists at Northwestern Medicine have developed a novel therapy to trick cancer cells into gobbling up what they think is their favorite food—cholesterol—which actually triggers their destruction. What appears to them as a cholesterol-loaded particle is actually a synthetic nanoparticle that binds to the cancer cells and starves them to death.
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Authored by Ningi AB*
Retroperitoneal tumours are an aggregate of multiple types of neoplastic lesions with a preponderance of tumours of mesenchymal origin. Other histological types such as Lymphoma, are reported to be commoner now. Retroperitoneal tumours are generally rare and clinical diagnosis is often difficult due its cryptic location. It is often diagnosed incidentally following abdominal radiological studies or following complications. The most common complication being an extrinsic compression, particularly, on the retroperitoneal structures; such as the ureters, duodenum or the major abdominal vessels. It may also present as a vague abdominal pain or chronic bowel obstruction like our index patient. Abdominal CT Scan is the most sensitive tool of diagnosis and complete surgical excision often, an enbloc excision with involved adjoining organs offers the best chance of cure. Adjuvant chemotherapy, radiotherapy or chemo-radiation improve disease free interval and overall survival. The mainstay of retroperitoneal lymphoma is however a cytotoxic chemotherapy or more recently Rituximab combination therapy. We present a case of a huge retroperitoneal large B-cell Lymphoma presenting as chronic small bowel obstruction.