Hey you. You know you should be doing The Thing. I don't want to do The Thing, either. But we can sit down and do it for 2 minutes together. Then we can do it for 5 minutes. Then 10. And so on and so forth until it is done. I'll be coming back to reiterate this.
To whoever needs to hear it: it does not have to be perfect. It does not have to be world altering. It just needs to be done. And I'll sit with you while you do The Thing.
Now go. Stop scrolling. Go work on The Thing. I'll be back to check on you and cheer us both on.
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Scientists have discovered a new way to destroy cancer cells. Stimulating aminocyanine molecules with near-infrared light caused them to vibrate in sync, enough to break apart the membranes of cancer cells.
Aminocyanine molecules are already used in bioimaging as synthetic dyes. Commonly used in low doses to detect cancer, they stay stable in water and are very good at attaching themselves to the outside of cells.
Continue Reading.
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At the centre of Rosalind Franklin’s tombstone in London’s Willesden Jewish Cemetery is the word “scientist”. This is followed by the inscription, “Her research and discoveries on viruses remain of lasting benefit to mankind.”
As one of the twentieth century’s pre-eminent scientists, Franklin’s work has benefited all of humanity. The one-hundredth anniversary of her birth this month is prompting much reflection on her career and research contributions, not least Franklin’s catalytic role in unravelling the structure of DNA.
. . .
But Franklin’s remarkable work on DNA amounts to a fraction of her record and legacy. She was a tireless investigator of nature’s secrets, and worked across biology, chemistry and physics, with a focus on research that mattered to society. She made important advances in the science of coal and carbon, and she became an expert in the study of viruses that cause plant and human diseases. In essence, it is because of Franklin, her collaborators and successors, that today’s researchers are able to use tools such as DNA sequencing and X-ray crystallography to investigate viruses such as SARS-CoV-2.
. . .
Franklin was an inveterate traveller on the global conference circuit and a collaborator with international partners. She won a rare grant (with Klug) from the US National Institutes of Health. She was a global connector in the booming early days of research into virus structures: an expert in pathogenic viruses who had gained an international reputation and cared deeply about putting her research to use.
It is a travesty that Franklin is mostly remembered for not receiving full credit for her contributions to the discovery of DNA’s structure. That part of Franklin’s life story must never be forgotten, but she was so much more than the “wronged heroine”, and it’s time to recognize her for the full breadth and depth of her research career.
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god im gonna be rewatching this games video for sure. it has everything. debating whether angela could beat people up. amanda faith in angela to beat people up. paul rudd fuckability ranking. shayne on nerd vs jock scale. chanse correctly pegging shayne as a nerd. angela and courtney swapping jackets. courtney describing the new bg3 kisses while angela goes :O. tomey bones presence and commentary. amanda dunking on shayne. does "cheat on your wife" count as advice. courtney: "if you guys win this im eating my own asshole on camera." the entire other team: Insta 1HKO. shayne: *silent kermit nod* amanda: "REALLY? :D" . angela making a strong joke and then immediately bailing out with "i wish i hadn't done that" and everyone at the table breaking. "you guys scared me into being ugly :(((((". excellent. no notes.
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2024-04-26
It’s been a long week, and there’s even longer ones to come.
But what is there to do?
What is there to do but to keep going?
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I've been considering making this post for a while but hesitated since I don't wanna beat a dead horse.
I'd like you to look at this post looking back at the Andijan massacre. What started as people protesting issues like distribution of gas, electricity, and other human needs and rights ended in a bloodbath. A cousin of mine told me schools taught it as "the national guard protecting civilians from Islamist terrorists."
I'd also like you to look at this paper by the Human Rights Watch on the torture and persecution of Uzbek Muslims like me during Islam Karimov's 20 years of dictatorial rule. Even Uzbek Muslims outside of Uzbekistan weren't safe. Multiple family friends of mine were randomly tackled to the ground and arrested by Korean Police on accounts of "domestic terrorism" in Uzbekistan, and some were only released about 5 years ago.
You weren't allowed to wear hijabs(even in Islamic universities), openly pray, read the Quran, or do anything religious. Someone would always be there watching to report you.
I wasn't allowed to go outside by myself around my neighborhood due to Uzbek government agents kidnapping the children of Uzbek diaspora abroad. I wasn't allowed to wear a hijab until after we went to Uzbekistan 2 years after Karimov's regime ended, and we made sure it was safe there and back. I wasn't even allowed to visit the country to see my relatives for almost a decade because of the crackdown on Uzbek Muslims.
When Uzbekistan was colonized by Russia as the Uzbek SSR and even before then as Turkestan, Russia made sure to stamp out religion entirely. They killed off scholars and poets like Cholpon, who wrote about Uzbek self-determination and praised religious texts. Uzbekistan's first leadership since its independence carried on with this policy, with Russian colonial values ingrained into them.
As for Korea, our partition was opposed by the whole peninsula. When Jejuans protested the US-UN backed elections, it ended in 10% of Jeju's population being killed by joint US-Korean forces. Though the South Korean Government apologized for the first time recently, the US stays silent. What a surprise. The bodies of these Jejuans were buried in mass pits and had the Jeju Airport built on top of it.
The US still fails to apologize for the No Gun Ri Massacre, in which the US Army murdered about 300 Korean villagers despite knowing they were civilians and therefore not targets. The US also indiscriminately bombed North Korea with more bombs than they had in the Pacific Theater in World War 2, martyring almost 2 million Koreans.
After the Korean War followed almost 30 years of dictatorship by Syngman Rhee, then a military junta, then Park Chung Hee and Chun Doo Hwan. During this time, university students protesting the dictatorial rule established by the US were arrested as "anti communists," and be tortured repeatedly, sometimes even until death.
Though the Seodaemun Prison is known for being Japan's colonial prison where they arrested independence activists, the Korean dictatorships used it to arrest people in favor of democracy.
The Namyeong-Dong Anti-Communist Investigation Office was a similar prison, in which one of the floors had extremely thin, narrow windows to avoid prisoners from escaping. Park Jong Cheol, a Seoul National University student who was protesting against Korea's military dictatorship at the time, was incarcerated here and routinely tortured. He eventually died due to water torture.
The Gwangju Massacre was a protest held by many activists against Chun Doo Hwan's dictatorial rule, which came about as he staged a coup and successfully overthrew the previous government. As they called for democracy, Chun Doo Hwan brought the national army, who fired upon, killed, and raped the protesters. Chun Doo Hwan was never held responsible for his crimes before he died, and his grandson recently apologized to the victims and their loved ones. It was found that the US approved Chun Doo Hwan's plans to use armed forces on the protesters in Gwangju.
Though the Gwangju Massacre is taught about in Korea, much of the US involvement and responsibility of the horrors of the dictatorship is left out.
The US does not allow Korea to produce its own nuclear arsenal, allowing Korea to rely entirely on the US for nuclear support. Additionally, the existing presence of the USFK in Korea and their joint training sessions with the ROK army further provokes North Korea and therefore gives the US a "justification" to maintain its military presence in Korea.
Growing up I was taught where to look for nearby nuclear shelters. We visited the War Memorial of Korea multiple times, and air raid sirens are rare but are happening more often recently.
This, along with the added danger of living as Uzbek diaspora outside of Uzbekistan as Muslims.
So when I say "please respectfully depict Russia and the US when it comes to the Cold War in a way that does not center them entirely" and "please keep the gravity of their actions in mind as you write them; Hetalia does not exist in an apolitical vacuum,"
and I am met with "mature adults" telling me that "they're just characters," or
"i'm the one ruining the fandom," or
"block and move on," or
"i love russia and america cold war!!!" or
"you're crazy" or
"moralf*g" or
"someone's sensitive"
and especially from russian artists who call me an "American SJW." russians calling me an uzbek overly sensitive for asking that they portray their country a little more respectfully to the victims of their colonialism. yeah that's completely normal
you are normalizing centering discussions about the Cold War to the imperial core, and then having nothing of substance to say about and being absolutely insensitive towards someone who's life has been and still are dictated by these imperial forces, and even harrassing them.
where's the "block and move on" mentality you prided yourselves for?
this fandom hasn't changed since the 2010s. it's just more quiet in the way it marginalizes victims of colonialism.
oh, and that person who told me to "block and move on, sister!!!" when it comes to me explaining myself as an uzbek-korean muslim?
you're not one to talk. 네가 뭘아는데 ㅅㅂ새끼야
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Exploring the Marvels of Biological Macromolecules: The Molecular Machinery of Life (Part 3)
Proteins and Enzymes: Catalysts of Molecular Reactions
Proteins are the central players in macromolecular interactions. Enzymes, a specialized class of proteins, catalyze biochemical reactions with remarkable specificity. They bind to substrates, facilitate reactions, and release products, ensuring that cellular processes occur with precision.
Protein-Protein Interactions: Orchestrating Cellular Functions
Proteins often interact with other proteins to form dynamic complexes. These interactions are pivotal in processes such as signal transduction, where cascades of protein-protein interactions transmit signals within cells, regulating diverse functions such as growth, metabolism, and immune responses.
Protein-Ligand Interactions: Molecular Recognition
Proteins can also interact with small molecules called ligands. Receptor proteins, for instance, bind to ligands such as hormones, neurotransmitters, or drugs, initiating cellular responses. These interactions rely on specific binding sites and molecular recognition.
Protein-DNA Interactions: Controlling Genetic Information
Transcription factors, a class of proteins, interact with DNA to regulate gene expression. They bind to specific DNA sequences, promoting or inhibiting transcription, thereby controlling RNA and protein synthesis.
Membrane Proteins: Regulating Cellular Transport
Integral membrane proteins participate in macromolecular interactions by regulating the transport of ions and molecules across cell membranes. Transport proteins, ion channels, and pumps interact precisely to maintain cellular homeostasis.
Cooperativity and Allosteric Regulation: Fine-Tuning Cellular Processes
Cooperativity and allosteric regulation are mechanisms that modulate protein function. In cooperativity, binding one ligand to a protein influences the binding of subsequent ligands, often amplifying the response. Allosteric regulation occurs when a molecule binds to a site other than the active site, altering the protein's conformation and activity.
Interactions in Signaling Pathways: Cellular Communication
Signal transduction pathways rely on cascades of macromolecular interactions to transmit extracellular signals into cellular responses. Kinases and phosphatases, enzymes that add or remove phosphate groups, play pivotal roles in these pathways.
Protein Folding and Misfolding: Disease Implications
Proteins must fold into specific three-dimensional shapes to function correctly. Misfolded proteins can lead to Alzheimer's, Parkinson's, and prion diseases. Chaperone proteins assist in proper protein folding and prevent aggregation.
References
Voet, D., Voet, J. G., & Pratt, C. W. (2016). Fundamentals of Biochemistry: Life at the Molecular Level. Wiley.
Lehninger, A. L., Nelson, D. L., & Cox, M. M. (2017). Lehninger Principles of Biochemistry. W. H. Freeman.
Berg, J. M., Tymoczko, J. L., & Stryer, L. (2002). Biochemistry. W. H. Freeman
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༻`` 18 Apr 24 — Thursday 14/60
🧡 academia >> studied for 45 mins and wanted more but I'm proud of myself for what I've done! (actually, it's more like 1hr 40 because of my math revision in class!!)
🧡 physical health >> I took a rest day because my back and shoulder are sore and I don't want it to get worse with my bad form
🧡 self care >> I'm still trying to fix my posture whenever I remember it
☀️ 7.l5🌙 23.05
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Scrolling through Pinterest and Tumblr to find inspiration to study and promptly not studying because inspiration (?)
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One of those "is it worth it" debates i find myself having with myself is about mental health related posts that may make good points otherwise but subscribe heavily to and reference and frame mental illness through the biomedical model and the widespread (but false) idea that a chemical imbalance causes these issues. Comprehensive explanation for this + resources here. (Also worth looking into this activist's work where she describes what paychiatric gaslighting looks like)
The thing is I do not want to spread that misinformation anymore. It was presented to me as fact despite there being little proof of it, for a long time in my life from psychology teachers to therapists to psychiatrists of course. Just treated as a natural fact when it was literally pseudoscience on the same level as most rudimentary psychoanalysis.
So I have to make the decision to either simply not reblog it and therefore not engage with the wider mental health discourse and let people be mistaken from what is possibly just an honest mistake as something that has been taught to us all so so largely, they very well might just honestly not know it not be true, and then by leaving it alone I am letting that myth perpetuate from well-meaning people...
Or...
I actually correct the person, get a bunch of people who find their worldview so suddenly challenged being angry about it and calling me anti science as often happens and get retraumatised over my experiences with Psychiatric abuse at large.
And although I mostly choose the former and simply don't engage it leaves me feeling uneasy because I know I was that person once who didn't think to question the validity of chemical imbalance theories and if someone had told me about it honestly it would have saved me a world of pain. But too many people are progressive only on the surface and hate to have to consider abolitionist approaches to oppressive systems, too many people genuinely believe a host of more stigmatised symptoms and disorders to be deserving of incarceration or erasure, and i have no way of knowing who these people would be. And this is why pop psychology and liberal mental health advocates have run the anti-psych movement into the shadows - a movement to which we owe every step of our liberation as mentally ill people.
So how do you make this a bigger conversation again?
Like. Tell me this isn't blatantly a mass misinformation campaign at this point
[linked here]
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Scientists have discovered a remarkable new way to destroy cancer cells. Stimulating aminocyanine molecules with near-infrared light caused them to vibrate in sync, enough to break apart the membranes of cancer cells.
Aminocyanine molecules are already used in bioimaging as synthetic dyes. Commonly used in low doses to detect cancer, they stay stable in water and are very good at attaching themselves to the outside of cells.
Continue Reading.
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10.09.23. tuesday.
Sorry, it’s been a while. Stuff has happened since I last logged in here and I’m considering making a youtube channel, but I’m not sure if I wanna link it to this tumblr straight away. But, if I do make a youtube channel, it will be about
taking care of one’s mental health as a neurodivergent student (bonus if ur in stem, cuz I am, hehe)
MORE adhd studying tips
my other passions that don’t include studying (before stem, I’ve always been more inclined to art.)
If that sounds like your cup of tea, I hope you’ll like my channel! I might even start a podcast about these things as well, as I think having a talk about mental health especially as someone with depression and anxiety who’s trying really hard to do right by her studies is something many can relate to.
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Chemistry behind cod liver oil
"Fish oil" and "cod liver oil" are common nutritional health products and many people confuse these two, or even consider them as the same products. In fact, the effects of fish oil and cod liver oil are totally different. The main components of fish oil are DHA and EPA, which we introduced a few days ago. DHA is important for the development and maintenance of brain and nervous tissue; EPA can be used to treat autoimmune disorders and prevent cholesterol and fat from building up in artery walls.
Cod liver oil is a dietary supplement derived from the liver of cod fish (Gadidae). The main ingredients are retinol and cholecalciferol. Retinol is an important component of photosensitive substances in visual cells and can also maintain the integrity and health of epithelial tissue structure. Cholecalciferol promotes calcium absorption, as well as phosphorus reabsorption by renal tubules.
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